Key ingredients
4.7/5
Adapalene 0.1% is the main active in this gel.
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Adapalene Gel 0.1% 45g Pump
$23.97
Differin 0.1% adapalene gel is the default leave-on retinoid for acne. The 45g pump is the value size when you already know you tolerate it.
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The Edyt Score
4.7 / 5.0
Targets
4.7/5
This gel is for OTC retinoid.
Formula standards
4.7/5
The formula is an OTC retinoid.
The verdict
This gel suits OTC retinoid.
Compare against similar products
Side-by-side vs 6 near substitutes (La Roche-Posay, PanOxyl, TARO, Proactiv, AcneFree, and Glenmark Therapeutics) — best for, key actives, texture, skin fit, Edyt score, and notes. Swipe sideways to compare.
| Pick | |||||||
|---|---|---|---|---|---|---|---|
| Best for | Proven OTC adapalene | Derm-brand shoppers | First adapalene trial | Generic value | Proactiv users | Drugstore backup | Lowest-cost generic |
| Key actives | Adapalene 0.1% | Adapalene 0.1% | Adapalene 0.1% | Adapalene 0.1% | Adapalene 0.1% | Adapalene 0.1% | Adapalene 0.1% |
| Texture | Gel | Gel | Gel | Gel | Gel | Gel | Gel |
| Skin fit | Acne-prone skin | Acne-prone / sensitive-leaning | First-time adapalene users | Acne-prone skin | Acne-prone skin | Acne-prone skin | Acne-prone skin |
| Edyt score Methodology: The Edyt Score reflects ingredient profiles, concentration, and formulation standards. It is separate from crowd-sourced user reviews. | 4.7 | 4.5 | 4.4 | 4.4 | 4.2 | 4.2 | 4.1 |
| Notes | OTC retinoid · Pump | Effaclar · 0.1% | Leave-on · Starter | USP · Paraben-free claim | ProactivMD · 0.1% | Once-daily · OTC | Generic · Value |
| $ / size | $23.97 | $39.99 | $11.04 | $19.99 | $30.60 | $22.27 | $8.49 |
| Shop | Buy on AmazonThis page | Buy on AmazonProduct page | Buy on AmazonProduct page | Buy on AmazonProduct page | Buy on AmazonProduct page | Buy on AmazonProduct page | Buy on AmazonProduct page |
FAQ
Who is Adapalene Gel 0.1% 45g Pump best for?
Differin 0.1% adapalene gel is the default leave-on retinoid for acne. The 45g pump is the value size when you already know you tolerate it.
How did Edyt Beauty score this gel?
Edyt Beauty rates Adapalene Gel 0.1% 45g Pump 4.7 out of 5 from the ingredient list, who it is for, and how the formula is built. That is separate from crowd-sourced user reviews.
How does it compare to similar products?
The compare table above stacks Adapalene Gel 0.1% 45g Pump against near substitutes for the same shopping job, including picks from La Roche-Posay, PanOxyl, TARO, Proactiv, AcneFree, and Glenmark Therapeutics. For more from the same brand, see More from Differin below.
Where can I buy it?
Shop Adapalene Gel 0.1% 45g Pump with the Buy on Amazon button when it is available. We may earn a commission from qualifying purchases. Prices and availability can change. You can also find it in our guide to 7 Best Adapalene Gels.
You may also like
La Roche-Posay
Effaclar Adapalene Gel 0.1%
$39.99
PanOxyl
Adapalene 0.1% Leave-On Gel
$11.04
TARO
Adapalene 0.1% USP Gel
$19.99
Proactiv
MD Adapalene Gel Acne Treatment
$30.60
AcneFree
Adapalene Gel 0.1%
$22.27
Glenmark Therapeutics
Adapalene Gel 0.1%
$8.49