See label is the main active in this angular cheilitis cream.
Home/ Brands/ Neosporin/ Lip Health Overnight Renewal Therapy
Lip Health Overnight Renewal Therapy
$11.30
Neosporin's petrolatum-based treatment is meant to work overnight, letting vitamins, lipids, and peptides sink in while your body does its natural repair work. Clinical testing showed visibly healthier lips in three days. The twin pack gives you a backup, and the tub format makes it easy to apply a generous layer before bed.
We may earn a commission from qualifying purchases.
The Edyt Score
4.6 / 5.0
This angular cheilitis cream is for neosporin's petrolatum-based treatment.
The formula is a petrolatum based.
The verdict
Neosporin's petrolatum-based treatment is meant to work overnight, letting vitamins, lipids, and peptides sink in while your body does its natural repair work.
Compare against similar products
Side-by-side vs 6 near substitutes (terrasil, Calmoseptine, O'Keeffe's, FixMySkin, MediBalm, and CareAll). Compare best for, key actives, texture, skin fit, Edyt score, and notes. Swipe sideways to compare.
| Pick | |||||||
|---|---|---|---|---|---|---|---|
| Best for | healing dry corners while you sleep | stubborn corner cracks needing extra help | moisture-related irritation at the corners | people who need a non-greasy finish | inflammation that needs calming down | anyone wanting relief within a day | simple protection at a low price |
| Key actives | See label | See label | See label | See label | See label | See label | See label |
| Texture | Cream | Cream | Cream | Cream | Cream | Cream | Cream |
| Skin fit | Dry | - | - | Dry | Dry | Dry | - |
| Edyt score Methodology: The Edyt Score reflects ingredient profiles, concentration, and formulation standards. It is separate from crowd-sourced user reviews. | 4.6 | 4.7 | 4.7 | 4.5 | 4.5 | 4.5 | 4.4 |
| Notes | Petrolatum based · Twin pack | Dermatologist tested · Fragrance free | Zinc oxide · Menthol | Medicated · Matte finish | Dermatologist developed · Gluten free | Hydrocortisone · Coconut oil | Zinc oxide · Budget friendly |
| $ / size | $11.30 | $19.95 | $8.79 | $8.99 | $15.00 | $7.45 | $4.24 |
| Shop | Buy on AmazonThis page | Buy on AmazonProduct page | Buy on AmazonProduct page | Buy on AmazonProduct page | Buy on AmazonProduct page | Buy on AmazonProduct page | Buy on AmazonProduct page |
FAQ
Who is Lip Health Overnight Renewal Therapy best for?
Neosporin's petrolatum-based treatment is meant to work overnight, letting vitamins, lipids, and peptides sink in while your body does its natural repair work. Clinical testing showed visibly healthier lips in three days. The twin pack gives you a backup, and the tub format makes it easy to apply a generous layer before bed.
How did Edyt Beauty score this angular cheilitis cream?
Edyt Beauty rates Lip Health Overnight Renewal Therapy 4.6 out of 5 from the ingredient list, who it is for, and how the formula is built. That is separate from crowd-sourced user reviews.
How does it compare to similar products?
The compare table above stacks Lip Health Overnight Renewal Therapy against near substitutes for the same shopping job, including picks from terrasil, Calmoseptine, O'Keeffe's, FixMySkin, MediBalm, and CareAll. For more from the same brand, see More from Neosporin below.
Where can I buy it?
Shop Lip Health Overnight Renewal Therapy with the Buy button when it is available. We may earn a commission from qualifying purchases. Prices and availability can change. You can also find it in our guide to Best Creams for Angular Cheilitis.
You may also like

terrasil
Skin Repair Ointment
$19.95

Calmoseptine
Ointment
$8.79

O'Keeffe's
Lip Repair Seal & Heal Medicated Lip Balm
$8.99

FixMySkin
1% Hydrocortisone Healing Lip Balm
$15.00

MediBalm
for Dry Cracked Lips - Healing Lip Balm for Severely Chappe…
$7.45

CareAll
Zinc Oxide 20% Skin Protectant Barrier Ointment
$4.24








