Peptide 21 is a peptide serum with hyaluronic acid. A silky firming layer, not a rich cream.
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For All Skin Types
$65.00
PTR Peptide 21 aims for a smoother look with a serum slip that doesn’t feel like balm. Better for normal-to-combo than very dry cheeks.
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The Edyt Score
4.4 / 5.0
For normal-to-combination skin that wants a smoother look. Skip it if cheeks are very dry and need a balm.
A serum slip, a few drops under moisturizer. It will not replace a retinoid if lines are the main ask.
The verdict
A decent peptide serum. One bottle.
Compare against similar products
Side-by-side vs 6 near substitutes (The Ordinary, The Inkey List, Paula's Choice, Drunk Elephant, Naturium, and RoC) — best for, key actives, texture, skin fit, Edyt score, and notes. Swipe sideways to compare.
| Pick | |||||||
|---|---|---|---|---|---|---|---|
| Best for | Peptide 21 serum | The Ordinary Multi-Peptide + HA is | Budget peptide serum | Paula’s Choice Peptide Booster lets you | Cult cream peptide serum | Naturium’s multi-peptide complex is | RoC’s Multi Correxion moisturizers fold |
| Key actives | Peptides · HA | Peptides · HA | Peptides · Collagen AAs | Peptides | Peptides · Waterlily | Peptides · Amino acids | Peptides |
| Texture | Peptide serum | Peptide serum | Peptide serum | Peptide serum | Peptide serum | Peptide serum | Peptide serum |
| Skin fit | Most skin types | — | — | — | — | — | — |
| Edyt score Methodology: The Edyt Score reflects ingredient profiles, concentration, and formulation standards. It is separate from crowd-sourced user reviews. | 4.4 | 4.5 | 4.4 | 4.6 | 4.5 | 4.5 | 4.3 |
| Notes | Silky · Brand staple | Budget cult · Layerable | Budget · Gel serum | Booster · Concentrated | Cult cream · Rich | Lightweight · Modern | Drugstore · Value |
| $ / size | $65.00 | $19.90 | $13.00 | $59.00 | $72.00 | $24.88 | $22.49 |
| Shop | Buy on AmazonThis page | Buy on AmazonProduct page | Buy on AmazonProduct page | Buy on AmazonProduct page | Buy on AmazonProduct page | Buy on AmazonProduct page | Buy on AmazonProduct page |
FAQ
Who is For All Skin Types best for?
PTR Peptide 21 aims for a smoother look with a serum slip that doesn’t feel like balm. Better for normal-to-combo than very dry cheeks.
How did Edyt Beauty score this peptide serum?
Edyt rates For All Skin Types 4.4 out of 5 based on formula fit for at-home nail looks — who it is built for and how it performs in paint or press kits — not star averages or paid placement.
How does it compare to similar products?
The compare table above stacks For All Skin Types against near substitutes for the same shopping job, including picks from The Ordinary, The Inkey List, Paula's Choice, Drunk Elephant, Naturium, and RoC. For more from the same brand, see More from Peter Thomas Roth below.
Where can I buy it?
Shop For All Skin Types with the Buy button when it is available. We may earn a commission from qualifying purchases. Prices and availability can change. You can also find it in our guide to Best Peptide Serums.
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Paula's Choice
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Drunk Elephant
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Naturium
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RoC
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