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Home/ Guides/ best numbing creams for microneedling
7 Best Numbing Creams for Microneedling to Start With
Published 10/07/2026
If you've got a derma stamp or a pen sitting in a drawer, numbing cream is usually the next search. They're the plain lidocaine creams from the drugstore aisle, nothing exotic, and the differences between them come down to texture, how long they take, and how much of the feeling they actually take away. This guide looks at what people tend to like about certain formulas and where the limits are.
Our top picks
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Best 5% with vitamin E
ZensaNumbing Cream 5% Lidocaine - Maximum Strength Topical Anesthetic with Vitamin E
$39.99
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Compare the best
Side-by-side tradeoffs for this shortlist, best for, key actives, texture, skin fit, Edyt score, and notes. Same picks; swipe sideways to compare.
| Pick | |||||||
|---|---|---|---|---|---|---|---|
| Best for | A 5% cream that names itch and irritation | A 2 oz jar at 5% | A 5% cream whose page leads with hemorrhoids | A 6 oz 5% jar labeled for hemorrhoids | Two 1.25 oz tubes at 5% | A 4% cream for minor burns and bites | A 5% relief cream under the name |
| Key actives | 5% lidocaine · Allantoin · Vitamin E | 5% lidocaine | 5% lidocaine · Vitamin E | 5% lidocaine | 5% lidocaine | 4% lidocaine · Arnica · Emu oil | 5% lidocaine |
| Texture | Cream | Cream | Cream | Cream | Cream | Oil | Cream |
| Skin fit | External pain relief | External pain relief | Hemorrhoid label | Hemorrhoid label | External pain relief | Minor burns and bites | External relief |
|
Edyt score
Methodology: The Edyt Score reflects a comprehensive analysis of ingredient profiles, concentration levels, and formulation standards. It is an objective technical evaluation of the product's composition, separate from crowd-sourced user reviews. | 4.6 | 4.5 | 4.3 | 4.2 | 4.5 | 4.3 | 4.2 |
| Notes | Aloe | 2 oz jar | - | 6 oz | Two tubes | - | Relief |
| $ / size | $14.24 | $9.99 | $39.99 | $18.36 | $24.22 | $9.99 | $19.98 |
| Shop | Buy on AmazonRead review | Buy on AmazonRead review | Buy on AmazonRead review | Buy on AmazonRead review | Buy on AmazonRead review | Buy on AmazonRead review | Buy on AmazonRead review |
Our picks, explained
Best labeled 5% cream
Ebanel 5% Lidocaine Numbing Cream
5% lidocaine with allantoin, vitamin E, and aloe.
Ebanel prints 5% lidocaine, with allantoin, vitamin E, and aloe. The page says the cream is for temporary relief of pain, burning, itching, and minor skin irritation, and it also mentions postpartum and hemorrhoid relief. Five percent is the figure people circle in this search. The labeled uses are broader than a facial routine, so the box is the instruction, not a microneedling guide.
Why it makes the list
- The cream is 5% lidocaine.
- Allantoin, vitamin E, and aloe are on the page.
What to keep in mind
- The page also names hemorrhoid and postpartum relief.
- Maximum-strength wording is the over-the-counter lidocaine cap, not a facial protocol.
Best 2 oz 5% jar
Curist 5% Lidocaine Numbing Cream Pain Relief (2 oz Jar)
5% lidocaine in a 2 oz jar.
Curist is 5% lidocaine in a 2 oz jar, sold as pain relief, anti-itch, and numbing cream. The page calls 5% the strongest lidocaine strength sold over the counter. Two ounces is a modest jar, which is a reasonable first size if you are only checking how your skin reacts. The label is a pain cream. It does not describe a roller or a needle.
Why it makes the list
- The jar is 2 oz of 5% lidocaine.
- The page sells it as pain, itch, and numb relief.
What to keep in mind
- Two ounces goes quickly if you apply a thick layer.
- The label does not mention microneedling.
Best 5% with vitamin E
Zensa Numbing Cream 5% Lidocaine - Maximum Strength Topical Anesthetic with Vitamin E
5% lidocaine with vitamin E. The page leads with hemorrhoid relief.
Zensa is 5% lidocaine with vitamin E, and the product title leads with hemorrhoid symptom relief: pain, burning, and anorectal irritation. It also says vegan and cruelty-free. Five percent is on the label. The first use named on the page is hemorrhoids, which is worth reading twice if you found this jar through a microneedling search.
Why it makes the list
- The cream is 5% lidocaine with vitamin E.
- The title leads with hemorrhoid symptom relief.
What to keep in mind
- The labeled use is hemorrhoids and anorectal irritation.
- The price is the high end of this group for a single tube.
Best 6 oz 5% jar
WELMATE 5% Lidocaine Numbing Cream
5% lidocaine, 6 oz, labeled for hemorrhoids.
WELMATE is 5% lidocaine in a 6 oz size, and the page calls it a hemorrhoid cream for itching and burning from anorectal irritation. Six ounces is the large jar here. The percent matches the 5% tubes, and the labeled body area on this page is specific. Size alone is not a reason to move a hemorrhoid cream onto the face.
Why it makes the list
- The cream is 5% lidocaine at 6 oz.
- The page labels it for hemorrhoids and anorectal irritation.
What to keep in mind
- The labeled use is hemorrhoids, not the face.
- Six ounces is more cream than a small test area needs.
Best two-tube 5% pack
Clinical Resolution Numb Master 5% Lidocaine Numbing Cream
5% lidocaine, two 1.25 oz tubes. The page says 3 to 5 minutes.
Numb Master is 5% lidocaine in two 1.25 oz tubes. Clinical Resolution says a liposomal formula starts to numb in 3 to 5 minutes, peaks around 20 to 25 minutes, and is for pain, burning, and itching. Those times are the brand's claim for this cream as a topical anesthetic. They are not instructions for covering skin before needles. Two tubes is a backup if the first one is still in date.
Why it makes the list
- The pack is two 1.25 oz tubes at 5% lidocaine.
- The page says numbing starts in 3 to 5 minutes for pain, burning, and itching.
What to keep in mind
- The timing on the page is the brand's pain-relief claim, not a needling plan.
- A liposomal cream can feel occlusive on oily skin.
Best 4% tube
YYSDMVY Lidocaine 4% Numbing Cream
4% lidocaine for minor burns, cuts, scrapes, and insect bites.
YYSDMVY prints 4% lidocaine, not 5. The page lists minor burns, sunburn, cuts, scrapes, insect bites, and itching, and it mentions arnica and emu oil. Four percent is a step under the 5% jars if you are comparing the number on the carton. The uses named here are minor skin irritation. Treat the percent as 4 when you line the bottles up.
Why it makes the list
- The label is 4% lidocaine.
- The page names minor burns, cuts, scrapes, and insect bites.
What to keep in mind
- 4% is lower than the 5% jars on this page.
- Arnica and emu oil are extra ingredients if you only wanted lidocaine.
Best 5% Hempvana tube
Hempvana Lidocaine 5% Relief Cream
The title says lidocaine 5% relief cream.
Hempvana's title says lidocaine 5% relief cream, maximum strength, for numbing irritation. That 5% is the number on the product name, which is the same percent as Ebanel and Curist. The page title does not spell out a jar size in the short name, so check the ounce count on the carton when it arrives. Maximum strength here means the over-the-counter lidocaine figure, the same way the other 5% creams use it.
Why it makes the list
- The title prints lidocaine 5%.
- The product is sold as a relief cream.
What to keep in mind
- The short title does not state the ounce size.
- Maximum strength is the 5% over-the-counter figure, not a procedure dose.
How we made this list
We shortlisted 7 picks for numbing creams for microneedling. Each one had to clear the same bar: a clear job fit, an Edyt Score from our editorial breakdown, and enough brand diversity that the list isn’t one house repeated seven times.
- Define the job. If you've got a derma stamp or a pen sitting in a drawer, numbing cream is usually the next search.
- Diversify brands. One hero SKU per brand unless a second lane clearly earns its spot.
- Score the formula. Rankings use Edyt’s editorial breakdown (ingredients, target fit, finish, and use case).
- Cut near-clones. When two SKUs told the same story, we kept the stronger score or clearer use case.
FAQ
Who is this numbing cream list for?
People comparing over-the-counter lidocaine percents. Check the labeled use on each jar. Some of these pages name hemorrhoids, burns, or itch.
How did Edyt Beauty score these picks?
We weighted the lidocaine percent printed on the title, the jar size, and whether the page states a use such as itch, burns, or hemorrhoids.
How do the top picks compare?
Ebanel is 5% lidocaine with allantoin, vitamin E, and aloe, labeled for pain, burning, and itching. Curist is 5% in a 2 oz jar. Zensa is 5% with vitamin E, and the page leads with hemorrhoid relief. WELMATE is 5% at 6 oz, also labeled for hemorrhoids and anorectal irritation. Clinical Resolution Numb Master is 5% in two 1.25 oz tubes, and the page says numbing starts in 3 to 5 minutes for pain, burning, and itching. YYSDMVY is 4% for minor burns, cuts, scrapes, and insect bites. Hempvana's title says Lidocaine 5% Relief Cream.
Is this medical advice?
Edyt Beauty ranks over-the-counter products for comfort and formula fit only. This is not a diagnosis or treatment plan. See a clinician for flares, infection, or anything that does not improve.
Where should I buy them?
Use the Buy buttons on this page when a product is in stock. Prices and availability can change. Check the product page before you buy.
This is general beauty guidance, not medical advice. Patch-test new products if you have sensitive skin or known allergies.
Affiliate disclosure: we may earn a commission from links on this page. Prices and availability change.